Tuesday, July 31, 2018

Preeclampsia Foundation 2019 Peter Joseph Pappas Research Grant

Today the Preeclampsia Foundation issues a call for Letters of Intent for its 2019 Peter Joseph Pappas Research Grants program designed to accelerate preeclampsia research. The ultimate goal of the grant program is to drive research that will eliminate the delivery of pre-term babies as an intervention for severe preeclampsia, HELLP syndrome, and related hypertensive disorders of pregnancy. Named for the infant son of preeclampsia survivor Lauren Pappas and her husband Clement, the program awards grants totaling up to $200,000 each year.

The Preeclampsia Foundation awarded its 2018 grant earlier this year to Kent Thornburg, PhD, and his team at the Center for Developmental Health, Knight Cardiovascular Institute Oregon Health & Science University (OHSU), in Portland, Oregon, for his research proposal called “Targeted High-Throughput Methylome Analysis of Early and Late Onset Preeclampsia.”

Investigators meeting the program’s criteria are invited to submit Letters of Intentfor 2019 proposals by September 10, 2018. Letters of Intent that are of interest to the scientific review committee and the Preeclampsia Foundation’s Board of Directors will then be invited to submit full applications by November 2, 2018, with award decisions rendered in December 2018.

In addition to meeting the fund’s goals, preference will be given to proposals that use or build upon data available through The Preeclampsia Registry™ (self-reported, whole exome sequenced, and clinical data), or that will produce data or biological materials that can be added to the Registry’s data/bio repository. In addition to utilizing the Registry and its rich assets, proposals must align with the Preeclampsia Foundation’s vision of a world where preeclampsia no longer threatens the lives of mothers and their babies. Examples of such proposals include but are not limited to mechanisms for improved diagnosis, better prediction of who may be severely affected, therapeutic interventions to halt, reverse, or prevent the placental and organ dysfunction associated with the condition, and postpartum and long-term care of preeclampsia, eclampsia, and HELLP syndrome survivors.

“Three years ago we lost our son Peter due to preeclampsia following a 29-week delivery,” explained Lauren Pappas. “Since then we have dedicated our lives to helping others avoid the same outcome by establishing the Peter Joseph Pappas Fund.”

“Thanks to generous contributions from family and friends, and our partnership with the Preeclampsia Foundation, we are making strides to reach our ultimate goal of eliminating pre-term births due to preeclampsia by 2050,” added Clement Pappas.

The Peter Joseph Pappas Research Grants program adds to the Preeclampsia Foundation’s portfolio of research programs including the Vision Grant program for young investigators, PRIME for health services research, EMPOWER, which helps build research capacity in low- and middle-income countries, and The Preeclampsia Registry, a dynamic database of research participants including preeclampsia and HELLP syndrome survivors, family members, and controls (unaffected individuals).

Complete details can be found online at www.preeclampsia.org/research/research-funding. Letters of intent are due by Monday, September 10, 2018, via email to PJPGrants@preeclampsia.org.

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